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1.
An. bras. dermatol ; 90(3,supl.1): 178-180, May-June 2015. ilus
Article in English | LILACS | ID: lil-755766

ABSTRACT

Abstract

Piloleiomyoma is an uncommon benign neoplasm arising from the erector pilorum muscle. It presents as reddish-brown papules or nodules, in general located on the limbs or trunk, often painful. The present paper describes a case of piloleiomyoma with segmental distribution on left trunk, with an important expression of pain.

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Subject(s)
Adult , Humans , Male , Leiomyoma/pathology , Skin Neoplasms/pathology , Smooth Muscle Tumor/pathology , Dermis/pathology , Pain/etiology
2.
Braz. J. Psychiatry (São Paulo, 1999, Impr.) ; 30(3): 222-226, set. 2008. ilus, graf, tab
Article in English | LILACS | ID: lil-493776

ABSTRACT

OBJECTIVE: Typical antipsychotic drugs, mainly phenothiazines, have been associated with cataract formation for over forty years. Recently, there has been a concern about atypical antipsychotic drugs' potential for inducing this lenticular pathology. Accordingly, we sought to determine the cataract rate and other ocular side effects in patients on long-term therapy with antipsychotic drugs. METHOD: Eighty outpatients with DSM-IV diagnosis of schizophrenia from two settings who met pre determined inclusion criteria were submitted to an ophthalmological evaluation for ocular abnormalities with emphasis in the lens and cornea. They were divided into two groups: group 1 (n = 52) comprised patients who had been predominantly on typical antipsychotics for at least two years and group 2 (n = 28) patients who had been predominantly on atypical antipsychotics for at least two years. RESULTS: Cataract was found in 26 patients (33 percent) with predominance of anterior capsular cataract. The cataract rate among patients from group 1 (40 percent) was higher than among those from group 2 (18 percent). Visual acuity was reduced in 21 patients (26 percent). No changes were observed neither in the cornea nor in the retina. CONCLUSIONS: Patients using antipsychotic drugs should be submitted to a periodic ophthalmological evaluation.


OBJETIVO: Os antipsicóticos típicos, principalmente as fenotiazinas, têm sido associados à formação de catarata há mais de quarenta anos. Nos últimos anos, tem existido um questionamento acerca do potencial dos antipsicóticos atípicos de induzir essa patologia lenticular. Neste estudo, buscamos determinar a taxa de catarata e de outros efeitos oculares adversos em pacientes em uso de antipsicóticos a longo prazo. MÉTODO: Oitenta pacientes tratados ambulatorialmente com diagnóstico de esquizofrenia segundo o DSM-IV, de dois centros, que preencheram os critérios de inclusão pré determinados foram submetidos a uma avaliação oftalmológica para pesquisa de alterações oculares com ênfase no cristalino e na córnea. Eles foram divididos em dois grupos: o grupo 1 (n = 52) era formado por pacientes que tinham usado predominantemente antipsicóticos típicos por pelo menos dois anos e o grupo 2 (n = 28) por pacientes que tinham usado predominantemente antipsicóticos atípicos por pelo menos dois anos. RESULTADOS: Catarata foi encontrada em 26 pacientes (33 por cento) com predomínio de catarata capsular anterior. A taxa de catarata entre os pacientes do grupo 1 (40 por cento) foi maior do que naqueles do grupo 2 (18 por cento). A acuidade visual estava reduzida em 21 pacientes (26 por cento). Não foram encontradas alterações nem na córnea nem na retina. CONCLUSÕES: Pessoas em uso de antipsicóticos devem ser submetidas à avaliação oftalmológica periódica.


Subject(s)
Adolescent , Adult , Female , Humans , Male , Middle Aged , Young Adult , Antipsychotic Agents/adverse effects , Cataract/chemically induced , Schizophrenia/drug therapy , Antipsychotic Agents/classification , Cornea/drug effects , Diagnostic and Statistical Manual of Mental Disorders , Epidemiologic Methods , Visual Acuity , Young Adult
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